Sabtu, 26 Maret 2011

[M790.Ebook] Free Ebook Project Management for the Pharmaceutical Industry, by Laura Brown, Tony Grundy

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Project Management for the Pharmaceutical Industry, by Laura Brown, Tony Grundy

The pharmaceutical industry has encountered major shifts in recent years, both within the industry, and in its external environment. The cost of healthcare rising due to an ageing population, the intensification of regulatory requirements and mergers within the industry have led to an increased need for restructuring, cost reduction and culture change projects. Project management is the key to addressing these needs, and also to effective drug development. Given the costs of development and the critical issue of 'time to market', project management techniques - appropriately used - are a key factor in bringing a drug to market. In this book, Laura Brown and Tony Grundy's pharmaceutical expertise and experience offers the reader a guide to the most relevant project management tools and techniques and how to rigorously apply them in the pharmaceutical industry. The authors cover the technical, strategic and human aspects of project management, including contingency planning, simulation techniques and different project options. Complete with decision-tree diagrams, checklists, exercises and a full glossary, Project Management for the Pharmaceutical Industry provides clinical research, drug development and quality assurance managers or directors with a one-stop reference for successfully managing pharmaceutical projects. The text has been revised for this edition and now includes some additional material on risk management.

  • Sales Rank: #901005 in Books
  • Brand: Brand: Gower
  • Published on: 2011-06-28
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.75" h x 7.00" w x 1.00" l, .0 pounds
  • Binding: Hardcover
  • 298 pages
Features
  • Used Book in Good Condition

Review
'A comprehensive set of tools and techniques...The techniques and advice can be applied to many projects in the pharmaceutical industry, including drug development. This is particularly useful for managers who are looking to gain a new perspective for maximising project success...The importance of taking account of behavioural aspects for the successful running of pharmaceutical projects, often overlooked, is included...Above all, the case studies illustrate excellent techniques and principles to help the reader understand, and learn to use, modern tools and techniques for maximising management success. ' - Dr Carol Casman, Group Head, Transnational, Clinical Pharmacology and Discovery Medicine, GSK

About the Author
Laura Brown, BSc, PhD, MBA, Diploma in Clinical Science, is a Director of LB Training and Development, an independent management consultancy and training organisation for the pharmaceutical industry. She is Director of the MSc programme in Clinical Research, School of Pharmacy at the University of Cardiff. She is also Director of TOPRA's MSc in Regulatory Affairs. Laura has 20 years' experience of the pharmaceuticals industry and has worked with GSK, Hoechst Marion Roussel, Good Clinical Research Practices and MDS. She has worked as a Life Cycle Project Manager, Clinical Research Manager, and as Head of Training for a pharmaceutical training company. Laura is co-author of five books on management and is author of the latest SCRIP report in GCP. Tony Grundy, MA, MBA, MSc, MPhil, FCA and PhD is co-Director of Cambridge Corporate Development, and is Visiting Lecturer in Corporate Strategy and Corporate Finance at Henley Business School. He is also academic advisor on TOPRA's MSC in Regulatory Affairs. Tony has researched the strategic and financial appraisal of major projects, and the strategic behaviour of teams involved in complex projects. He specialises in strategic thinking, strategic team working, and project appraisal in a variety of contexts, and has also consulted extensively in the pharmaceutical industry. Tony is author of 17 books.

Most helpful customer reviews

5 of 5 people found the following review helpful.
Old school project management
By jps_fire
Pros: has a few useful tips on how to handle complex pharma issues, such as strategic planning and aligning business objectives to clinical development. The checklists in the appendix are helpful as a starting point, but require customization and modernization to today's settings.

Cons: This book is full of errors and typos, which makes one question the validity of the methods proposed. Also, it proposes some old-school methodologies that are not used in the modern pharma setting. It could benefit from an editor's review and an update to the 21st century.

0 of 0 people found the following review helpful.
Thrown together
By K. Olive
This book is an atrocity - it is full of spelling and grammatical errors, and poorly worded sentences that make no sense. I have the kindle version, so there is a chance the spelling errors are only on that version.

Another reviewer stated that the authors are "old school project management" and I have to agree. There are many books out there on project management, several related to the pharma industry, and these authors seem to be stuck in some old modalities of PM methodology.

And as ridiculous as it sounds, they misquoted a Spice Girls song - I mean, that's an easy google search to make sure you have the right lyrics. It just seems like this book was thrown together.

0 of 0 people found the following review helpful.
I think it would have been an excellent book however if I had some previous experience to ...
By l.m.
Only two starts because I couldn't relate it since I've never manages a project. I had to take this course for school. I think it would have been an excellent book however if I had some previous experience to draw from. The book did a good job asking questions to make you think and apply what your learning.

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Jumat, 25 Maret 2011

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Spite,Malice and Revenge: The Ultimate Guide to Getting Even (3 Diabolical Volumes in 1) Hardcover - December 28, 1988, by M. Nelson Chund

  • Sales Rank: #8809009 in Books
  • Published on: 1605
  • Binding: Hardcover

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[J944.Ebook] Fee Download Swimming to Antarctica: Tales of a Long-Distance Swimmer, by Lynne Cox

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Swimming to Antarctica: Tales of a Long-Distance Swimmer, by Lynne Cox

Now in paperback, with photos and maps added especially for this new edition, here is the acclaimed life story of a woman whose drive and determination inspire everyone she touches.

Lynne Cox started swimming almost as soon as she could walk. By age sixteen, she had broken all records for swimming the English Channel. Her daring eventually led her to the Bering Strait, where she swam five miles in thirty-eight-degree water in just a swimsuit, cap, and goggles. In between those accomplishments, she became the first to swim the Strait of Magellan, narrowly escaped a shark attack off the Cape of Good Hope, and was cheered across the twenty-mile Cook Strait of New Zealand by dolphins. She even swam a mile in the Antarctic.

Lynne writes the same way she swims, with indefatigable spirit and joy, and shares the beauty of her time in the water with a poet's eye for detail. She has accomplished yet another feat--writing a new classic of sports memoir.

  • Sales Rank: #194684 in Books
  • Brand: Mariner Books
  • Published on: 2005-03-07
  • Released on: 2005-03-07
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.00" h x .97" w x 5.31" l, .82 pounds
  • Binding: Paperback
  • 359 pages
Features
  • Lynne Cox
  • memoir
  • sports

Amazon.com Review
Just about every other person in the world seems like an unfocused dilettante compared to long-distance swimming legend Lynne Cox. Soon At the age of 14, after several years of training hard in pools and the open sea, she was swimming the 26 mile stretch from Catalina Island to the coast of California. A year after that, she surpassed a lifelong goal by not only swimming the English Channel but setting a new men's and women's record in the process. Rather than be satisfied, Cox aimed still higher, conquering the Cook Strait in New Zealand, the Strait of Magellan and, the Cape of Good Hope, none of which had been swum before. Being the first to swim the Bering Sea from Alaska to what was then the Soviet Union is perhaps Cox's most impressive achievement, requiring a phenomenal amount of physical strength and endurance to withstand the chilly waters and diplomatic persistence to gain permission from Gorbachev during the Cold War. Swimming to Antarctica is Cox's remarkably detailed account of her major swims and all that went right and wrong with them. While there are plenty of highs, as one might expect in a memoir by so impressive an athlete, all is not sunshine and roses for Cox. She overcomes extreme physical hardship, predatory sharks, and a swim through a sewage-soaked Nile while suffering from dysentery. There is plenty in Swimming to Antarctica to encourage even non-swimmers to work hard to achieve the seemingly impossible, but Cox, a skilled and highly readable writer, sticks to the swimming, leading the reader by example. For thrills and inspiration, it's hard to find anyone better than Lynne Cox. --John Moe

From Publishers Weekly
Cox, one of the world's leading long-distance swimmers, has been a risk-taker ever since she was nine and chose the freezing water of a New Hampshire pool in a storm over getting out and doing calisthenics. After her family moved to California so she and her siblings could train as speed swimmers, she discovered long-distance ocean swimming. Her first open-water event, a team race across the Catalina Channel, convinced her to train for the English Channel. At 15, she broke the Channel record, and decided she needed a new goal. Up to this point, Cox's story reads like a fairy tale of hard work, careful planning and good support, crowned with success. It isn't until she competes in the Nile River swim that the tale turns ugly-she's swimming in raw sewage and chemical waste, fending off the dead rats and broken glass, so sick with dysentery she lands in the hospital. Undeterred, she plans more ambitious swims-around the shark-infested Cape of Good Hope, across Alaska's Glacier Bay-to prepare for her big dream, a swim from Alaska to the Soviet Union across the Bering Strait. While offering herself to researchers studying the effects of cold on the human body, her political goals are even larger: to bring countries and peoples together, using swimming "to establish bridges between borders." Cox ends her story with her swim to Antarctica, where she finishes the first Antarctic mile in 32-degree water in 25 minutes. Even though readers know she survived to tell the tale, it's a thrilling, awesome and well-written story.
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

From Bookmarks Magazine
As this inspiring memoir makes clear, swimming is Cox's life. "Cox is not just in the sea," notes the Rocky Mountain News, "she is one with it." Cox offers intimate glimpses into her mind as she conquers icy (Antarctic) or rat-strewn (Nile) waters--her doubts, joys, and observations of unfamiliar surroundings. It's a compelling narrative, but critics disagree on a few points. Is her writing poetic or reportorial? Does she offer a complete or one-sided picture of her life? Where's the larger historical perspective? Quibbles aside, Cox successfully and joyfully captures the mental, physical, and political (think: America, Russia, Bering Strait) battles she overcomes each time she jumps into new waters. "As far as I knew," she writes, "I would only be here once, and I wanted to live as much as I could."

Copyright © 2004 Phillips & Nelson Media, Inc.

Most helpful customer reviews

28 of 28 people found the following review helpful.
Focus on the accomplishment, not the pain
By bensmomma
Lynne Cox is such an inspirational writer that the reader concentrates on her exceptional accomplishments, both physical and mental, rather than the extreme pain and struggle it took to accomplish them. From her early teens, Cox has eliminated almost everything else from her life to dedicate herself to open-water swims in treacherous and freezing waters, including crossing the Bering Straight between Alaska and the Soviet Union, and swimming a mile in the Antarctic Ocean.

What I really loved about this book is the way Cox struggled not only with the physical challenges of the swims but also struggled to make the swims mean something more to the world at large. For example, the Bering Straight swim took something lik 16 years of meetings and negotiations to arrange, hundreds of donors and volunteers. But in the end that swim stood as a testament and metaphor for the improving connections between nations. Everywhere she goes, Cox seems to have inspired anyone fortunate enough to witness her. That this has come with a great deal of personal sacrifice--money troubles, social limitations, significant nerve damage--is humbly underplayed in the book. She has a kind of determination and self-confidence that transcends a particular athletic endeavour.

That Cox does not *look* like anyone's idea of an endurance athlete just adds to the inspiration -- she's 45 and she's swimming to Antarctica...so what's MY excuse?

13 of 13 people found the following review helpful.
Very cold bath
By Lynn Hamilton
As a chubby nine-year-old, Lynne Cox was the slowest kid in the pool. But she loved swimming, so she kept plugging away at it. When the coach ordered her class out of the water because a storm was brewing, she got permission to keep swimming. When hail started falling, Cox kept swimming-alone-in a pool full of ice.

Scientists would later determine that her unique ratio of muscle to body fat made her anomalously suited to swimming long distances in water so cold, it would kill an ordinary swimmer within minutes. At 15, Cox swam the English Channel, breaking the world record. The next year, she went back to England and broke the record again.

It would be a mistake to think that Cox's new autobiography, Swimming to Antarctica: Tales of a Long-Distance Swimmer, is of interest only to swimmers. In fact, the book has more in common with heroic literature of the ancient world-like Beowulf and The Odyssey-than with the typical athlete's success story. Like those ancient heroes, Cox isn't satisfied with races that have a designated course. Instead, she looks for unique athletic challenges that only she can overcome. That's why, at 17, she fell out of love with channel swimming and, instead, took on the unknown-swimming icy lakes, straits and channels that had been thought impossible for a swimmer to breach. Her famous 1987 swim across the Bering Sea from Alaska to the Soviet Union took 10 years to plan, and the water, in August, was barely above freezing.

Although Cox isn't a professional writer, she has a keen eye for details that turn an important life experience into an entertaining story. Readers will be amused, for instance, by the English cab driver who told Cox she was too fat to swim the Channel-as he was driving her to the beach for that express purpose.

While other athletes were wooed by corporate sponsors, Cox had to finance her own projects. Her story is a powerful account of clinging hard to a bigger dream.

23 of 26 people found the following review helpful.
Four Stars for the Author, One Star for the Editor
By Y. Zohar
As an avid swimmer and reader,this book was a bit of a disappointment for me. I truly admire the author's determination and swimming prowess but her character emerges as one dimensional, which I'm sure it is not. There is little reference to her non-swimming life. Am I to believe, for example, that she never had any romantic relationships all those years? Was her life entirely about long distance swimming? Where is she today, in her mid-forties?

I was also disappointed by the fact that there are no photos or maps ! How is that possible in such a book?

Also, I feel that least 50 pages of the current edition could have been dropped. I would like to have read more about Ms. Cox's training, nutrition, etc. I don't even know what she looks like (height, weight).

In short: good story, bad editor.

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Fortune Smiles: Stories, by Adam Johnson

NATIONAL BOOK AWARD WINNER | WINNER OF THE STORY PRIZE | LOS ANGELES TIMES BOOK PRIZE FINALIST | A NEW YORK TIMES NOTABLE BOOK | NAMED ONE OF THE TEN BEST BOOKS OF THE YEAR BY SAN FRANCISCO CHRONICLE, USA TODAY, AND MIAMI HERALD | NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The Washington Post • NPR • Marie Claire • St. Louis Post-Dispatch • BuzzFeed • The Daily Beast • Los Angeles Magazine • The Independent • BookPage • Kirkus Reviews

Winner of the Pulitzer Prize for his acclaimed novel about North Korea, The Orphan Master’s Son, Adam Johnson is one of America’s most provocative and powerful authors. Critics have compared him to Kurt Vonnegut, David Mitchell, and George Saunders, but Johnson’s new book will only further his reputation as one of our most original writers. Subtly surreal, darkly comic, both hilarious and heartbreaking, Fortune Smiles is a major collection of stories that gives voice to the perspectives we don’t often hear, while offering something rare in fiction: a new way of looking at the world.

In six masterly stories, Johnson delves deep into love and loss, natural disasters, the influence of technology, and how the political shapes the personal. “Nirvana,” which won the prestigious Sunday Times short story prize, portrays a programmer whose wife has a rare disease finding solace in a digital simulacrum of the president of the United States. In “Hurricanes Anonymous”—first included in the Best American Short Stories anthology—a young man searches for the mother of his son in a Louisiana devastated by Hurricanes Katrina and Rita. “George Orwell Was a Friend of Mine” follows a former warden of a Stasi prison in East Germany who vehemently denies his past, even as pieces of it are delivered in packages to his door. And in the unforgettable title story, Johnson returns to his signature subject, North Korea, depicting two defectors from Pyongyang who are trying to adapt to their new lives in Seoul, while one cannot forget the woman he left behind.

Unnerving, riveting, and written with a timeless quality, these stories confirm Johnson as one of America’s greatest writers and an indispensable guide to our new century.

Praise for Fortune Smiles

“Masterful . . . Each [story] is a miniature demonstration of why his remarkable novel The Orphan Master’s Son won the 2013 Pulitzer Prize for fiction.”—The Washington Post

“[Johnson] is always perceptive and brave; his lines always sing and strut and sizzle and hush and wash and blaze over the reader.”—The New York Times Book Review

“Superb . . . explosive.”—The Wall Street Journal

“Remarkable . . . the best short story collection since Tenth of December . . . Johnson is one of America’s greatest living writers.”—The Huffington Post

“Haunting, harrowing . . . Johnson’s writing is as rich in compassion as it is in invention, and that rare combination makes Fortune Smiles worth treasuring.”—USA Today

“[Blends] exotic scenarios, morally compromised characters, high-wire action, rigorously limber prose, dense thickets of emotion, and, most critically, our current techno-moment.”—The Boston Globe

“Johnson’s boundary-pushing stories make for exhilarating reading.”—San Francisco Chronicle

“Entrancing.”—O: The Oprah Magazine




From the Hardcover edition.

  • Sales Rank: #13036 in Books
  • Published on: 2016-10-04
  • Released on: 2016-10-04
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.00" h x .70" w x 5.20" l, .81 pounds
  • Binding: Paperback
  • 336 pages

Review

“Masterful . . . Each [story] is a miniature demonstration of why his remarkable novel The Orphan Master’s Son won the 2013 Pulitzer Prize for fiction.”—The Washington Post
 
“[Adam Johnson] is always perceptive and brave; his lines always sing and strut and sizzle and hush and wash and blaze over the reader.”—The New York Times Book Review
 
“Superb . . . explosive.”—The Wall Street Journal
 
“Remarkable . . . the best short story collection since Tenth of December . . . Johnson is one of America’s greatest living writers.”—The Huffington Post
 
“Haunting, harrowing . . . Johnson’s writing is as rich in compassion as it is in invention, and that rare combination makes Fortune Smiles worth treasuring.”—USA Today
 
“Fortune Smiles [blends] exotic scenarios, morally compromised characters, high-wire action, rigorously limber prose, dense thickets of emotion, and, most critically, our current techno-moment.”—The Boston Globe
 
“Johnson’s boundary-pushing stories make for exhilarating reading.”—San Francisco Chronicle
 
“Entrancing.”—O: The Oprah Magazine
 
“One of the most original and compelling voices in contemporary American fiction.”—Entertainment Weekly
 
“Johnson packs more voice in his stories than most authors do in a novel.”—Esquire

“Stunning . . . Johnson is a writer of uncanny insight and compassion and Fortune Smiles is a wise, poignant and important book. It should not be missed.”—Toronto Star

“The best stories stretch well beyond their first and last words. They’re more than the opening scene; they invite the reader to imagine what came before and what will come after. They’re alive and they’re limitless. That’s exactly what the best stories in Fortune Smiles are like.”—NPR
 
“[A] bold and deeply wise collection.”—BuzzFeed
 
“Even as Johnson’s subject matter bends genre is a way that is assertively contemporary, much of his prose is classically beautiful. . . . The speculative fiction of Margaret Atwood and David Mitchell, which also trade in inherited traumas and personal resilience, come to mind, as do George Saunders’ darkly satiric visions of near-future America.”—The New Republic
 
“Transfixing . . . The collection amply confirms Johnson’s daring and talent.”—The Oregonian
 
“Excellent.”—Minneapolis Star Tribune

“Johnson has a rare combination of inventiveness, intellectual pyrotechnics and emotional sophistication. . . . These stories are treasures.”—BBC
 
“Adam Johnson returns with this riveting collection of short stories, each reflecting the darkly imagined, slightly surreal point of view that animated his Pulitzer Prize–winning novel, The Orphan Master’s Son. . . . He’s a compelling writer, in any form.”—San Jose Mercury-News

“Startlingly, blazingly original.”—BookPage

“[Adam Johnson] serves up six sinewy stories that shock and surprise in his edgy, inviting Fortune Smiles. . . . [They’re] compulsively readable tales about characters whose lives are largely ignored, undervalued, or simply uncharted and whose voices we seldom hear.”—Elle

“The stories in Fortune Smiles fizz with imagination, miniature worlds exploding onto the page. Adam Johnson’s prose is so pared-down, like the setting for precious stones, he gives us just what’s necessary to let the facets sparkle, without distraction. I loved this book!”—M. L. Stedman, New York Times bestselling author of The Light Between Oceans

“How do you follow a Pulitzer Prize–winning novel? For [Adam] Johnson, the answer is a story collection, and the tales are hefty and memorable. . . . In the title story, two North Korean criminals adjust to post-defection life in South Korea. . . . Often funny, even when they’re wrenchingly sad, the stories provide one of the truest satisfactions of reading: the opportunity to sink into worlds we otherwise would know little or nothing about.”—Publishers Weekly (starred review)

“A half-dozen sometimes Carver-esque yarns that find more-or-less ordinary people facing extraordinary challenges and somehow holding up. Tragedy is always close to the surface in Johnson’s work—with tragicomic layerings. . . . Bittersweet, elegant, full of hard-won wisdom: this is no ordinary book, either.”—Kirkus Reviews (starred review)




From the Hardcover edition.

About the Author

Adam Johnson is the author of The Orphan Master’s Son, winner of the Pulitzer Prize in fiction, the Dayton Literary Peace Prize, and the California Book Award, and finalist for the National Book Critics Circle Award. It was named one of the best books of the year by more than a dozen publications, including The Washington Post, The Wall Street Journal, the Los Angeles Times, and Entertainment Weekly. Johnson’s other awards include a Guggenheim Fellowship, a Whiting Writers’ Award, a National Endowment for the Arts Fellowship, and a Stegner Fellowship; he was also a finalist for the New York Public Library’s Young Lions Award. His previous books are Emporium, a short story collection, and the novel Parasites Like Us. Johnson teaches creative writing at Stanford University and lives in San Francisco with his wife and children.

Excerpt. © Reprinted by permission. All rights reserved.
It’s late, and I can’t sleep. I raise a window for some spring Palo Alto air, but it doesn’t help. In bed, eyes open, I hear whispers, which makes me think of the president, because we often talk in whispers. I know the whispering sound is really just my wife, Charlotte, who listens to Nirvana on her headphones all night and tends to sleep-­mumble the lyrics. Charlotte has her own bed, a mechanical one.

My sleep problem is this: when I close my eyes, I keep visualizing my wife killing herself. More like the ways she might try to kill herself, since she’s paralyzed from the shoulders down. The paralysis is quite temporary, though good luck trying to convince Charlotte of that. She slept on her side today, to fight the bedsores, and there was something about the way she stared at the safety rail at the edge of the mattress. The bed is voice-­activated, so if she could somehow get her head between the bars of the safety rail, “incline” is all she’d have to say. As the bed powered up, she’d be choked in seconds. And then there’s the way she stares at the looping cable that descends from the Hoyer Lift, which swings her in and out of bed.

But my wife doesn’t need an exotic exit strategy, not when she’s exacted a promise from me to help her do it when the time comes.

I rise and go to her, but she’s not listening to Nirvana yet—­she tends to save it for when she needs it most, after midnight, when her nerves really start to crackle.

“I thought I heard a noise,” I tell her. “Kind of a whisper.”

Short, choppy hair frames her drawn face, skin faint as refrigerator light.

“I heard it, too,” she says.

In the silver dish by her voice remote is a half-­smoked joint. I light it for her and hold it to her lips.

“How’s the weather in there?” I ask.

“Windy,” she says through the smoke.

Windy is better than hail or lightning or, God forbid, flooding, which is the sensation she felt when her lungs were just starting to work again. But there are different kinds of wind.

I ask, “Windy like a whistle through window screens, or windy like the rattle of storm shutters?”

“A strong breeze, hissy and buffeting, like a microphone in the wind.”

She smokes again. Charlotte hates being stoned, but she says it quiets the inside of her. She has Guillain-­Barré syndrome, a condition in which her immune system attacks the insulation around her nerves so that when the brain sends signals to the body, the electrical impulses ground out before they can be received. A billion nerves inside her send signals that go everywhere, nowhere. This is the ninth month, a month that is at the edge of the medical literature. It’s a place where the doctors no longer feel qualified to tell us whether Charlotte’s nerves will begin to regenerate or she will be stuck like this forever.

She exhales, coughing. Her right arm twitches, which means her brain has attempted to tell her arm to rise and cover the mouth. She tokes again, and through the smoke she says, “I’m worried.”

“What about?”

“You.”

“You’re worried about me?”

“I want you to stop talking to the president. It’s time to accept reality.”

I try to be lighthearted. “But he’s the one who talks to me.”

“Then stop listening. He’s gone. When your time comes, you’re supposed to fall silent.”

Reluctantly, I nod. But she doesn’t understand. Stuck in this bed, having sworn off TV, she’s probably the only person in America who didn’t see the assassination. If she’d beheld the look in the president’s eyes when his life was taken, she’d understand why I talk to him late at night. If she could leave this room and feel the nation trying to grieve, she’d know why I reanimated the commander in chief and brought him back to life.

“Concerning my conversations with the president,” I say, “I just want to point out that you spend a third of your life listening to Nirvana, whose songs are by a guy who blew his brains out.”

Charlotte tilts her head and looks at me like I’m a stranger. “Kurt Cobain took the pain of his life and made it into something that mattered. What did the president leave behind? Uncertainties, emptiness, a thousand rocks to overturn.”

She talks like that when she’s high. I tap out the joint and lift her headphones.

“Ready for your Nirvana?” I ask.

She looks toward the window. “That sound, I hear it again,” she says.

At the window, I peer out into the darkness. It’s a normal Palo Alto night—­the hiss of sprinklers, blue recycling bins, a raccoon digging in the community garden. Then I notice it, right before my eyes, a small black drone, hovering. Its tiny servos swivel to regard me. Real quick, I snatch the drone out of the air and pull it inside. I close the window and curtains, then study the thing: its shell is made of black foil stretched over tiny struts, like the bones of a bat’s wing. Behind a propeller of clear cellophane, a tiny infrared engine throbs with warmth.

“Now will you listen to me?” Charlotte asks. “Now will you stop this president business?”

“It’s too late for that,” I tell her, and release the drone. As if blind, it bumbles around the room. Is it autonomous? Has someone been operating it, someone watching our house? I lift it from its column of air and flip off its power switch.

Charlotte looks toward her voice remote. “Play music,” she tells it.

Closing her eyes, she waits for me to place the headphones on her ears, where she will hear Kurt Cobain come to life once more.

I wake later in the night. The drone has somehow turned itself on and is hovering above my body, mapping me with a beam of soft red light. I toss a sweater over it, dropping it to the floor. After making sure Charlotte is asleep, I pull out my iProjector. I turn it on, and the president appears in three dimensions, his torso life-­size in an amber glow.

He greets me with a smile. “It’s good to be back in Palo Alto,” he says.

My algorithm has accessed the iProjector’s GPS chip and searched the president’s database for location references. This one came from a commencement address he gave at Stanford back when he was a senator.

“Mr. President,” I say. “I’m sorry to bother you again, but I have more questions.”

He looks into the distance, contemplative. “Shoot,” he says.

I move into his line of sight but can’t get him to look me in the eye. That’s one of the design problems I ran across.

“Did I make a mistake in creating you, in releasing you into the world?” I ask. “My wife says that you’re keeping people from mourning, that this you keeps us from accepting the fact that the real you is gone.”

The president rubs the stubble on his chin. He looks down and away.

“You can’t put the genie back in the bottle,” he says.

Which is eerie, because that’s a line he spoke on 60 Minutes, a moment when he expressed regret for legalizing drones for civilian use.

“Do you know that I’m the one who made you?” I ask.

“We are all born free,” he says. “And no person may traffic in another.”

“But you weren’t born,” I tell him. “I wrote an algorithm based on the Linux operating kernel. You’re an open-­source search engine married to a dialog bot and a video compiler. The program scrubs the Web and archives a person’s images and videos and data—­everything you say, you’ve said before.”

For the first time, the president falls silent.

I ask, “Do you know that you’re gone . . . that you’ve died?”

The president doesn’t hesitate. “The end of life is another kind of freedom,” he says.

The assassination flashes in my eyes. I’ve seen the video so many times—­the motorcade slowly crawls along while the president, on foot, parades past the barricaded crowds. Someone in the throng catches the president’s eye. The president turns, lifts a hand in greeting. Then a bullet strikes him in the abdomen. The impact bends him forward, his eyes lift to confront the shooter. A look of recognition settles into the president’s gaze—­of a particular person, of some kind of truth, of something he has foreseen? He takes the second shot in the face. You can see the switch go off—­his limbs give and he’s down. They put him on a machine for a few days, but the end had already come.

I glance at Charlotte, asleep. “Mr. President,” I whisper, “did you and the first lady ever talk about the future, about worst-­case scenarios?”

I wonder if the first lady was the one to turn off the machine.

The president smiles. “The first lady and I have a wonderful relationship. We share everything.”

“But were there instructions? Did you two make a plan?”

His voice lowers, becomes sonorous. “Are you asking about bonds of matrimony?”

“I suppose so,” I say.

“In this regard,” he says, “our only duty is to be of service in any way we can.”

My mind ponders the ways in which I might have to be of service to Charlotte.

The president then looks into the distance, as if a flag is waving there.

“I’m the president of the United States,” he says, “and I approved this message.”

That’s when I know our conversation is over. When I reach to turn off the iProjector, the president looks me squarely in the eye, a coincidence of perspective, I guess. We regard each other, his eyes deep and melancholy, and my finger hesitates at the switch.

“Seek your inner resolve,” he tells me.

Can you tell a story that doesn’t begin, it’s just suddenly happening? The woman you love gets the flu. Her fingers tingle, her legs go rubbery. Soon she can’t grip a coffee cup. What finally gets her to the hospital is the need to pee. She’s dying to pee, but the paralysis has begun: the bladder can no longer hear the brain. After an ER doc inserts a Foley catheter, you learn new words—­axon, areflexia, ascending peripheral polyneuropathy.

Charlotte says she’s filled with “noise.” Inside her is a “storm.”

The doctor has a big needle. He tells Charlotte to get on the gurney. Charlotte is scared to get on the gurney. She’s scared she won’t ever get up again. “Please, honey,” you say. “Get on the gurney.” Soon you behold the glycerin glow of your wife’s spinal fluid. And she’s right. She doesn’t get up again.

Next comes plasmapheresis, then high-­dose immunoglobulin therapy.

The doctors mention, casually, the word ventilator.

Charlotte’s mother arrives. She brings her cello. She’s an expert on the siege of Leningrad. She has written a book on the topic. When Charlotte’s coma is induced, her mother fills the neuro ward with the saddest sounds ever conceived. For days, there is nothing but the swish of vent baffles, the trill of vital monitors, and Shostakovich, Shostakovich, Shostako­vich.

Two months of physical therapy in Santa Clara. Here are dunk tanks, sonar stimulators, exoskeletal treadmills. Charlotte becomes the person in the room who makes the victims of other afflictions feel better about their fate. She does not make progress, she’s not a “soldier” or a “champ” or a “trouper.”

Charlotte convinces herself that I will leave her for one of the nurses in the rehab ward. She screams at me to get a vasectomy so this nurse and I will suffer a barren future. To soothe her, I read aloud Joseph Heller’s memoir about contracting Guillain-­Barré syndrome. The book was supposed to make us feel better. Instead, it chronicles how great Heller’s friends are, how high Heller’s spirits are, how Heller leaves his wife to marry the beautiful nurse who tends to him. And for Charlotte, the book’s ending is particularly painful: Joseph Heller gets better.

We tumble into a well of despair that’s narrow and deep, a place that seals us off. Everything is in the well with us—­careers, goals, travel, children—­so close that we can drown them to save ourselves.

Finally, discharge. Yet home is unexpectedly surreal. Amid familiar surroundings, the impossibility of normal life is amplified. But the cat is happy, so happy to have Charlotte home that it spends an entire night curled on Charlotte’s throat, on her tracheal incision. Goodbye, cat! While I’m in the garage, Charlotte watches a spider slowly descend from the ceiling on a single thread. She tries to blow it away. She blows and blows, but the spider disappears into her hair.

Still to be described are tests, tantrums and treatments. To come are the discoveries of Kurt Cobain and marijuana. Of these times, there is only one moment I must relate. It was a normal night. I was beside Charlotte in the mechanical bed, holding up her magazine.

She said, “You don’t know how bad I want to get out of this bed.”

Her voice was quiet, uninflected. She’d said similar things a thousand times.

“I’d do anything to escape,” she said.

I flipped the page and laughed at a picture whose caption read, “Stars are just like us!”

“But I could never do that to you,” she said.

“Do what?” I asked.

“Nothing.”

“What are you talking about, what’s going through your head?”

I turned to look at her. She was inches away.

“Except for how it would hurt you,” she said, “I would get away.”

“Get away where?”

“From here.”

Neither of us had spoken of the promise since the night it was exacted. I’d tried to pretend the promise didn’t exist, but it existed.

“Face it, you’re stuck with me,” I said, forcing a smile. “We’re destined, we’re fated to be together. And soon you’ll be better, things will be normal again.”

“My entire life is this pillow.”

“That’s not true. You’ve got your friends and family. And you’ve got technology. The whole world is at your fingertips.”

By friends, I meant her nurses and physical therapists. By family, I meant her distant and brooding mother. It didn’t matter: Charlotte was too disengaged to even point out her nonfunctional fingers and their nonfeeling tips.

She rolled her head to the side and stared at the safety rail.

“It’s okay,” she said. “I would never do that to you.”

Most helpful customer reviews

77 of 80 people found the following review helpful.
Fortune Grimaces
By Ann Elliot
When this book appeared on the list of Vine possibilities, I jumped on it. The way my life has been going recently, I could use a little hope and cheer. The title sounded like just what I needed.

That will teach me to choose a book without doing any research first.

In the book, Fortune Smiles is the name of a rigged North Korea-based lottery game.

The six stories feature a woman paralyzed and in the throes of Guillain-Barre syndrome, a man fighting his compulsion to molest little girls, a woman with breast cancer, a UPS driver dealing with personal crises and the aftermath of hurricanes Katrina and Rita, a former Stasi warden of a notorious prison for political prisoners in what was East Berlin and two men who rather accidentally defected from North Korea to South Korea, where they trade a totalitarian regime for the equally not-subtle indoctrination of glitzy capitalism and proselytizing Christianity.

Fortune hasn't smiled on any of these characters, unless she is enjoying some very cruel pranks.

I avidly read all the stories anyway. Johnson is a highly skilled writer who pulls the reader into unfamiliar territory and unfolds a good bit of social commentary.

I even finished the story about child molesters, although my stomach was churning as I read.

One of my favorites was "Interesting Facts," the one narrated by a woman with breast cancer. It was deftly written--so much so that I stopped part way through and reread to see how Johnson had led me down the path he wished without my seeing what he was doing.

I also enjoyed "Hurricanes Anonymous" because, really, who could not like a young Cajun UPS driver who keeps delivering packages while accompanied by his 2-year-old son Geronimo in spite of the ravages of hurricanes Katrina and Rita? His deliveries to the zombielike refugees living in a former Chuck E. Cheese stayed with me for days.

The writing kept me reading. This is not a book everyone will want to read. In fact, I'm not sure I wanted to read it, but I'm glad I did.

3 of 3 people found the following review helpful.
A Universe of Imagination
By Fairbanks Reader - Bonnie Brody
I love to read short story collections and I usually don't connect with every story included. It was not different with this book. However, there were some stories that knocked me for a loop with their intelligence, subtlety and outright outrageousness. Adam Johnson is a wordsmith, a man with an imagination as big as the universe, a post-modernist and a traditionalist, a writer for all seasons.

The first story in the collection, 'Nirvana' is about a woman with Guillain-Barre syndrome. She is paralyzed by the disease and spends most of her waking time listening to Kurt Cobain. Her husband is a free source computer genius who has been able to bring to life a past president of the United States who has been assassinated in the past. He is able to talk to the president and the president answers him but only with phrases he's actually used when he was alive. Both husband and wife have experienced great loss and as the husband states, "This feeling of being in proximity to something that's lost to you, it seems like my whole life right now".

'Interesting Facts' is a story close to my heart. A young woman with children is going through treatment for breast cancer and the treatment is brutal. She often wonders what her husband would do should she succumb to the disease. What is particularly interesting, besides the narrative itself, is that the woman's husband has won a Pulitzer prize for a novel about North Korea, and he gets invited to all these functions with beautiful women. She worries if one of them will seduce him. I wonder how much of the author's real life is contained in this story.

There's a story of a UPS driver who 'inherits' a child after Hurricane Katrina, a story about an ex-Stasi prison guide, as well as a few others in this collection. They are all well-written and interesting. It is the above two, however, that spoke most personally to me.

4 of 4 people found the following review helpful.
Short stories admittedly aren’t my favorite thing to read
By Jessica Weil
Short stories admittedly aren’t my favorite thing to read. I often find they are anticlimactic or that they feel unfinished, and I can’t help but have a difficult time pouring myself into a story that I know will end so quickly. But Adam Johnson’s short story collection, Fortune Smiles, won the National Book Award, so I had a feeling I was in store for something special, and I was anything but disappointed.

The stories – distinctly melancholy, darkly funny, bleak and sometimes surreal – are thematically consistent: they’re about lonely people facing extraordinary challenges.

In Nirvana, a man’s wife has been stricken with Guillain-Barre syndrome, her entire body paralyzed for the past nine months. Struggling with his wife’s illness and her threat of suicide, he develops a program that allows him to speak to the hologram of a recently deceased president, and takes solace in his new confidant.

In Hurricanes Anonymous, a directionless young father takes care of his son in post-Katrina New Orleans.

In Interesting Facts, the ghost of a woman who died of breast cancer visits her family and worries about her husband moving on.

In George Orwell Was a Friend of Mine, a former Stasi prison warden is in denial about the atrocities committed under his watch, and eerily attempts to justify and rationalize torture as a necessary part of a functioning society.

In Dark Meadows – perhaps one of the most harrowing and disturbing stories I’ve ever read – a non-offending pedophile who himself was abused as a child helps the police track child pornography cases and finds himself looking after two neglected young girls in his neighborhood.

And finally, in Fortune Smiles, a man who defected from North Korea struggles to adapt to life in South Korea and dreams of returning to his home country.

The problem with many short story collections is that they are uneven. While some of the stories take hold of you, others are immediately forgettable. But with Fortune Smiles, almost every single story had me captivated – with the exception, perhaps, of Hurricanes Anonymous. If you enjoy short stories, don’t miss this collection. And even if you typically don’t, give it a try anyway.

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Kamis, 24 Maret 2011

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Essential Grammar for the iBT: Delta's Key to the Next Generation TOEFL Test, by Nancy Gallagher

Although the TOEFL iBT does not have a discrete grammar section, knowledge of English sentence structure is important throughout the test. Essential Grammar for the iBT reviews the skills that are fundamental to success on tests. Content includes noun and verb forms, clauses, agreement, parallel structure, punctuation, and much more. The book may be used in conjunction with the other texts in the Delta's Key to the Next Generation TOEFL Test series or as a standalone grammar text for intermediate and advanced students.

Features

  • 20 units covering vital points of sentence structure
  • Abundant practice in TOEFL-like questions
  • Listening texts on audio CD
  • Diagnostic test and review quizzes
  • Answer key, audio scripts, and index

  • Sales Rank: #348638 in Books
  • Brand: Brand: Delta Publishing Company(IL)
  • Published on: 2009-07-10
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.70" h x .70" w x 8.50" l, 1.40 pounds
  • Binding: Paperback
  • 308 pages
Features
  • Used Book in Good Condition

Most helpful customer reviews

0 of 0 people found the following review helpful.
Essential Grammar for the iBT
By Hanna Y
Great book where you will find grammar rules along with exercises. It will increase your level of English and help you prepare for your tests.

0 of 0 people found the following review helpful.
Four Stars
By Tin Pham
Good!!!

0 of 0 people found the following review helpful.
Five Stars
By Pornpong Wongpoonga
Thanks

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Selasa, 22 Maret 2011

[K561.Ebook] PDF Ebook The Pacific Northwest Gardener's Book of Lists, by Ray McNeilan, Jan McNeilan

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The Pacific Northwest Gardener's Book of Lists, by Ray McNeilan, Jan McNeilan

The Pacific Northwest Gardener's Book of Lists, by Ray McNeilan, Jan McNeilan



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The Pacific Northwest Gardener's Book of Lists, by Ray McNeilan, Jan McNeilan

The Pacific Northwest Gardener's Book of Lists is the definitive gardening guide for gardeners in this area. Included are such interesting lists as: annuals that attract beneficial insects, perennials for autumn color, hostas for full sun, annuals for dry shade, trees with weeping character, and more.

  • Sales Rank: #1512920 in eBooks
  • Published on: 1997-04-01
  • Released on: 2012-08-08
  • Format: Kindle eBook

Review
Dozens of plant lists citing a ppropriate choices with regard to all sorts of requirements, from the obvious (such as low-maintenance) to the esoteric (such as groundcovers for cracks and crevices). The books' authors also include ideas and suggestions on a vast range of topics from regional horticultural experts. Gardeners can never have too many plants. A list-lover's dream come true. (HortIdeas Magazine)

The format lends itself to quick problem-solving including what to plant in a difficult site, what to plant for winter interest, shrubs with berries or hostas that tolerate sun. The book is laced with quotes from local experts and avid amateur gardeners. (The Oregonian)

This is a must for local gardeners to add to their gardening library. (Garden Showcase)

...[this book's] basic premise is to share information on what works and what doesn't. Well-organized and handy. (The Redmond Spokesman)

...a wonderful resource book for Northwest gardeners. When you purchase the book, be sure to purchase two highlighter pens. You will run out of ink on the first pen about half-way through. (Liz Douville Bend Bulletin)

People love lists. They love the conciseness, the choices inherent in them, the straightforwardness. Now in one little book, you get more than 200 lists to answer almost any plant question you can come up with. This is definitely one book to put on your must-have list. (Oregonian)

Do we really need more lists? Yes, when they are as useful as those in The Pacific Northwest Gardener's Book of Lists. (Valerie Easton The Seattle Times)

The nifty book delivers just what its title promises: lots of lists that make gardening easier for folks who are lucky enough to live in the Pacific Northwest. (Nmpro Magazine)

Beginning gardeners, those new to the Northwest or anyone who likes seeing a range of options should check out this book. (Stefanie Knowlton, Statesman Journal)

Most helpful customer reviews

34 of 35 people found the following review helpful.
A must for the serious gardener.
By michaelsyvertsen@msn.com
Consult this book before you start your projects. As a master gardener it has been invaluable answering questions from the public. What species of tree can I plant in a wet land? What shrub can handle dark shade? Over 200 lists answering this type of question. Geared for the Puget Sound.

18 of 18 people found the following review helpful.
mixed feelings
By A Customer
In one sense, this book is great. If you want a list of plants that fit one certain criteria, just look for that list. The book is fairly easy to use in this sense, and that's why I gave it three stars; it seems like the authors spent a lot of time thinking about how to organize this book so you could find the list you were after.
The problem is that no one picks a plant based upon one single criteria. One could page back and forth to see which lists contain which plants, but that seems rather more complicated than simply reading the complete descriptions in your copy of Sunset's Western Garden Book.
Of course, you need to narrow your focus before diving into the Sunset book. And there is the dilemma. This book answers that dilemma, sort of. It offers a first step, a way to begin the process of elimination. But you'll drop this book immediately upon narrowing your focus. If, say, you're looking at the 13 trees in the "trees with fragrant blossoms" list and then proceed to the Sunset book to read complete descriptions of each tree you'll discover that one of the trees in the "fragrant blossoms" list (Southern Magnolia) is difficult or impossible to grow things underneath. You could also find this out by looking up "trees that are impossible to grow things underneath" in the Book of Lists, but you wouldn't know to do this without having already looked in the Sunset book. Confused yet?
Basically, this book offers one way to narrow the focus a little before you begin investigating specific plants. That's worth something, I guess. However, if you are expecting that you will be able to use this book to determine the right plant for a situation, it won't work for that.

0 of 0 people found the following review helpful.
Excellent and helpful book on northwest trees
By Rebecca Martin
This is a fantastic book. Besides excellent and whimsical lists of trees, the writer is entertaining. This is the tree book to buy if you are trying to select the right tree for the right spot or trying to not buy a tree that makes a mess in the fall, etc. Enjoy it as I do.

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Sabtu, 19 Maret 2011

[W698.Ebook] Ebook Free Theories of Personality, by Duane P. Schultz, Sydney Ellen Schultz

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Theories of Personality, by Duane P. Schultz, Sydney Ellen Schultz

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Theories of Personality, by Duane P. Schultz, Sydney Ellen Schultz

Filled with updated research and findings, Schultz and Schultz's THEORIES OF PERSONALITY, 11th Edition gives students a clear and cogent introduction to this dynamic field. Organized by theory, this popular text discusses major theorists who represent psychoanalytic, neopsychoanalytic, lifespan, trait, humanistic, cognitive, behavioral, and social-learning approaches, while demonstrating the influence of events in theorists' personal and professional lives on the development of their theories. The text reviews current work on selected facets of personality including locus of control, sensation seeking, learned helplessness, optimism-pessimism, and positive psychology. The authors also explore the ways in which race, gender, and cultural issues play a part in the study of personality and in personality assessment. The final chapter, "Personality in Perspective," integrates topics explored in previous chapters and suggests conclusions that can be drawn from the many theorists' work.

  • Sales Rank: #10628 in Books
  • Published on: 2016-01-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.10" h x .90" w x 7.90" l, .0 pounds
  • Binding: Hardcover
  • 496 pages

About the Author
Duane P. Schultz is a former professor of psychology at the University of South Florida. He has also held faculty appointments at the University of North Carolina at Charlotte, Mary Washington College of the University of Virginia (now the University of Mary Washington), American University in Washington, D.C., and the University of Groningen in the Netherlands. Dr. Schultz and his wife, Sydney Ellen Schultz, are a well-regarded textbook author team.

Sydney Ellen Schultz is a writer, editor, and researcher who has developed print and digital publications and teaching materials for publishers, government agencies, schools, and professional associations. She and her husband, Duane Schultz, are well regarded as textbook authors.

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Kamis, 17 Maret 2011

[D875.Ebook] PDF Download Life Is a Blessing: A Biography of Jerome Lejeune — Geneticist, Doctor, Father, by Clara Lejeune Gaymard

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Life Is a Blessing: A Biography of Jerome Lejeune — Geneticist, Doctor, Father, by Clara Lejeune Gaymard

Life Is a Blessing: A Biography of Jerome Lejeune — Geneticist, Doctor, Father, by Clara Lejeune Gaymard



Life Is a Blessing: A Biography of Jerome Lejeune — Geneticist, Doctor, Father, by Clara Lejeune Gaymard

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Life Is a Blessing: A Biography of Jerome Lejeune — Geneticist, Doctor, Father, by Clara Lejeune Gaymard

Book annotation not available for this title.
Title: Life Is a Blessing
Author: Lejeune-Gaymard, Clara/ Miller, Michael J. (TRN)/ Hilgers, Thomas W. (FRW)
Publisher: Univ of Chicago Pr
Publication Date: 2011/02/28
Number of Pages: 139
Binding Type: PAPERBACK
Library of Congress:

  • Sales Rank: #241726 in Books
  • Published on: 2011-02-28
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.00" h x .50" w x 5.50" l, .45 pounds
  • Binding: Paperback
  • 149 pages

Most helpful customer reviews

8 of 8 people found the following review helpful.
Life Starts From the Moment of Conception- A Geneticist Doctor Confirms!
By Liz Lantigua
Life Is a Blessing, is the biography of French geneticist, doctor and father, Jerome Lejeune. The book was written by his daughter Clara Lejeune-Gaymard.

Lejeune was known for discovering that the presence of an extra twenty-first chromosome causes Down Syndrome(trisomy 21). He went on to identify other chromosomal disorders. His passion was the welfare of the mentally challenged children.

What stood out the most in this biography was the factual information quoted from his own writings on how life begins at the moment of conception. He takes you from 2 or 3 days after fertilization when there is only one living cell with a description of how that living cell keeps forming. "Fifteen days after the period is missed.....His miniscule heart has been beating for a week already; his arms, his legs, his head, and his brain are already roughly formed...." WOW, it's a must read! If anyone has any doubt they should read this detailed book from this renowned doctor who flew to the United States to testify in a court case of divorce and frozen embryos. The case was in Maryville, Tennessee and Judge Dale Young gave judgement in the case and wrote "for American common law that men begin at fertilization."

Dr. Lejeune's life was inspiring in many ways. I highly recommend it!

3 of 3 people found the following review helpful.
Worth a Read on a Couple of Levels
By 1
I caught wind of Dr. Lejeune from a radio broadcast of a presentation by his daughter, the author. There are some awkward translations from the French here and there, but nothing that will confound the reader. The organization seems a bit haphazard at times, but it provides an endearing and memorable portrait of a man whom the author obviously loved deeply. If it were only that it would be worth a read, but it also outlines a man who shows how faith can act through science and scientists. I've been passing it along the folks I know who work in the medical field.

3 of 3 people found the following review helpful.
Excellent book!
By Dan Deeny
I recommend this book! It is easy to read and will encourage the reader to do good works. It is positive! This book can be read and reread!

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